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Lauri Urvas

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Jul 2026

Peptide ligand discovery of G protein-coupled receptors

This Primer outlines experimental and computational workflows tailored to peptide–GPCR interactions, including in silico peptide mining, deorphanization strategies, library-based screening platforms, modern pathway-resolved biosensor assays, and approaches for peptide stabilization and optimization strategies to address their pharmacokinetic limitations.

J. Hermes, Marin Matic, H. Yeung et al. · 0 citations