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Author

Lawrence J. Appel

3 papers indexed here

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Review Open access Sep 2026

Research Priorities to Accelerate Global Uptake of Lower Sodium Salt Substitutes.

BACKGROUND Excess sodium intake is a modifiable cause of elevated blood pressure and cardiovascular disease. Despite the World Health Organization's recommendation to limit sodium intake <2 g/d, average global consumption exceeds twice this amount. Replacing a portion of sodium chloride with potassium chloride in lower...

T. Brady, Kathy Trieu, Laura K. Cobb et al. · 0 citations
Sep 2026

Physical Performance and Risk of Heart Failure, Kidney Failure, and Mortality in CKD: Findings from the CRIC Study.

BACKGROUND Physical performance limitations are common in chronic kidney disease (CKD) and affect independence and survival, yet physical performance is not routinely assessed. We examined whether the Short Physical Performance Battery (SPPB), a multidimensional measure of lower-extremity physical performance, was long...

Devika Nair, Rebecca T. Brown, Michael G. Shlipak et al. · 0 citations
Open access Sep 2026

Blood Metabolomic Signatures of One-Hour Glucose Predict Cardiometabolic Risk

Background: Elevated 1-hour glucose levels during an oral glucose tolerance test (OGTT) strongly predict type 2 diabetes (T2D) and cardiovascular disease. We investigated whether fasting blood metabolome predicting 1-hour glucose could be a target for improving β-cell function, long-term glycemic trajectories, and redu...

Yoriko Heianza, Ming-Hao Kou, Xuan Wang et al. · 0 citations

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