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Author

Layla Panahipour

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2 papers indexed here

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Open access Sep 2026

Hemin suppresses interferon responses in periodontal cell models through JAK2–STAT1 inhibition

Introduction Hemin, an oxidized heme species released during erythrocyte breakdown, is detectable in gingival crevicular fluid during periodontal inflammation, but its effects on local immune signaling remain unclear. We investigated whether hemin modifies cytokine-induced interferon responses in HSC-2 oral squamous ce...

Xiao-Yu Huang, R. Gruber, Layla Panahipour · 0 citations
Open access Jul 2026

Transcriptomic profiling reveals selective attenuation of interferon-associated inflammatory signaling and induction of metallothioneins by a zinc-containing oral rinse

Findings identify a previously unrecognized host-modulatory activity of a zinc-containing Listerine® formulation characterized by selective attenuation of interferon-associated inflammatory transcription together with induction of a zinc-responsive metallothionein program.

Xiao-Yu Huang, Anna Podesser, M. Cengiz et al. · 1 citation · ⚡1

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