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Le-Chua Xiang

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Open access Aug 2026

DAAM1 formin and Ena/VASP proteins assemble functionally distinct actin filaments for focal adhesions

This study investigated how functionally distinct actin nanoscale layers, specified by α-actinin and tropomyosin isoforms, Tpm1.6 and Tpm3.2, are assembled at focal adhesions and found that DAAM1 formin assembles Tpm3.2-actin filaments, whereas Ena/VASP family proteins polymerize α-actinin cross-linked actin filament b...

Le-Chua Xiang, Parijat Biswas, H. Wioland et al. · 1 citation

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