Oct 2026
Immunoregulatory artificial lymph nodes restore antigen-specific tolerance in advanced multiple sclerosis.
Tolerogenic dendritic cell (tolDC) vaccines are a promising antigen-specific therapy for multiple sclerosis (MS), yet their efficacy is limited by poor homing to secondary lymphoid organs and rapid loss of the tolerogenic phenotype in native inflamed lymph nodes. Here, we developed a 3D-printed tolerogenic artificial l...
Jing-Sen Ji, Xin-Huan Wang, Lu Liu et al.
· Science Translational Medici... · 0 citations