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Lea Frideres

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Open access Jul 2026

A portable Cas6f-based system for multiplex translational repression in bacteria

MORTISE is introduced, a compact Cas6f-based RNA system to repress target bacterial genes without relying on host RNA factors, enables multiplex control across bacteria, and supports pathway balancing when genetic knockouts are unsuitable.

Giusi Favoino, Denis Pšenka, Lea Frideres et al. · Nature Communications · 0 citations