Double-Negative T Cells Induce Ferroptosis-Dependent, MHC-Independent Cytotoxicity of CD8+ T Cells Against AML 2256323
Acute myeloid leukemia (AML) is a blood cancer originating from myeloid cells in the bone marrow with poor prognosis. CD3+CD4-CD8-double negative T cells (DNTs) is a rare subset of immune cells that have shown strong anti-AML properties. Our previous work demonstrated that allogeneic DNTs from healthy donors effe...