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Author

Lei Cai

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Review Open access Sep 2026

Lymphopenia and mortality in adult sepsis: A systematic review and focused meta-analysis of prognostic evidence.

Lymphopenia-related phenotypes are associated with mortality in adult sepsis, but the small quantitative evidence base and moderate-to-substantial heterogeneity limit the precision and generalizability of the pooled effect.

Shi-Jie Cao, Lei Cai, Wei Zhang · 0 citations
Open access Jul 2026

Single-Cell Dissection of the Immune Microenvironment in Intrahepatic Metastasis of Multifocal Hepatocellular Carcinoma

Findings identify GPNMB-positive macrophages as key metabolic and immune regulatory hubs, suggesting that targeting the GPNMB–prostaglandin E2 axis provides a promising precision therapeutic strategy for intrahepatic metastasis in multifocal hepatocellular carcinoma.

Yuyan Xu, Cheng Zhang, Zhuo-Cheng Ji et al. · 0 citations

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