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Open access Aug 2026

Steering C-N coupling pathway on spatial-separated zinc dual sites for efficient oxime electrosynthesis

Multi-step cascade reactions that couple electrochemical and non-electrochemical steps are an appealing strategy for designing efficient reactions. However, their development is fundamentally constrained by mechanistic uncertainty, leading to uncontrolled side reactions. Herein, a spatially separated active-site strate...

Ru-Han Wang, S. Jia, Yu-Bin Hong et al. · 0 citations
Open access Aug 2026

Divergent Disassembly of PrP106-126 Aggregates Driven by Isomeric Polyoxometalate Hybrids.

The misfolding and aggregation of the prion protein into amyloid fibrils is primarily driven and stabilized by hydrophobic interactions, rendering the aggregates highly resistant to disaggregation and posing a significant therapeutic challenge. To address this issue, we design two compounds by covalently grafting isome...

Siyu Liang, Chenxi Zhang, Yanfei Lv et al. · 0 citations

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