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Author

Lei Qin

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Oct 2026

Iterative dissolved-oxygen control combined with growth-production coordination enables efficient erythritol biosynthesis in Yarrowia lipolytica under high-temperature stress.

A comprehensive understanding of the growth-production trade-off under heat stress is essential for developing high-yield thermotolerant chassis. Here, the effects of elevated temperature on growth and erythritol biosynthesis were systematically investigated in YL (A high-erythritol-producing industrial Yarrowia lipoly...

Jin-Wei Zhang, Rui-Zeng Cao, Rui-Xi Xue et al. · 0 citations
Sep 2026

Metabolic Engineering Strategies for High-Level α-Pinene Production in Saccharomyces cerevisiae

α-Pinene is a biologically active monoterpene compound derived from coniferous plants, performing multiple ecological and physiological functions. Moreover, its strained bicyclic skeleton makes it an exceptional renewable feedstock for high-density renewable fuels. However, the extraction of α-pinene from plants is a...

Ya-Peng Zhang, Wen-Qiang Li, Jian-Wen Wang et al. · 0 citations
Open access Jul 2026

Evolutionary Origins and Synthetic Reconstruction of Gingerols

The evolutionary logic by which plants recruit and coordinate novel enzymatic activities to establish lineage-restricted metabolic program is revealed, providing a framework for understanding and engineering specialized metabolism across the plant kingdom.

Wei-Hao Wang, Qingmin Li, Jun Zhang et al. · 0 citations

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