Lei Shen

Divergent Synthesis of Heterocycles through Cascade Rearrangements of Dienyne-Amides and Dialkyl Bromomalonates

Divergent synthesis provides efficient access to structurally diverse molecules from common precursors. Herein, we report a catalyst- and temperature-controlled cascade rearrangement of dienyne-amides with dialkyl bromomalonates, enabling selective access to three distinct N,O-heterocyclic scaffolds. Gold catalysis a...