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Lei Shi

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Review Open access Aug 2026

Improving recombinant protein productivity in CHO cells via multi-omics data integration

Chinese hamster ovary (CHO) cells represent the dominant host system for the production of recombinant therapeutic proteins. In recent decades, extensive research has focused on process/media optimization and cell line engineering to improve both the productivity and quality of biopharmaceutical proteins produced in CH...

Yuan Shen, Lei Shi, Xi Zhang et al. · 0 citations

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