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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Lei Tang

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Sep 2026

Discovery of a highly selective FLT3-ITD inhibitor with potent antileukemic activity based on 4-(2-fluorophenoxy)pyridine scaffold.

Acute myeloid leukemia (AML) driven by FLT3-ITD mutations remains a therapeutic challenge with limited treatment options. Herein, we report the design, synthesis, and biological evaluation of a series of 4-(2-fluorophenoxy)pyridine derivatives featuring an imidazolidinone carboxamide linker as potent FLT3-ITD inhibitor...

Zhong-Yuan Wang, Yi-Wei Zhang, Lin Li et al. · 0 citations
Sep 2026

Discovery of quinoline-based derivatives as c-Met inhibitors for the treatment of non-small cell lung cancer.

The design, synthesis, and biological evaluation of a novel series of type II c-Met inhibitors bearing α-amino acid-derived linkers and a morpholinopropoxy quinoline scaffold position compound 41 as a promising lead for the development of next-generation, tolerable c-Met targeted therapeutics.

Zhong-Yuan Wang, Yi-Wei Zhang, Yun-Feng Wang et al. · 0 citations

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