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Author

Lei Wang

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Aug 2026

Mas receptor activation promotes mitophagy and preserves neuronal function after traumatic brain injury.

Findings identify MasR as an endogenous regulator of PINK1/Parkin-mediated mitophagy and mitochondrial homeostasis following TBI and demonstrate that MasR signaling is required for preserving mitochondrial function and neurological outcomes after injury.

Rui-Li Dang, Lei Wang, Changshui Wang et al. · 0 citations
Open access Sep 2026

Cerebral endothelial cell-derived exosomes target injury sites to rescue cerebral energy crisis after traumatic brain injury

In murine TBI models, CEC-Exos alleviated cerebral glucose hypometabolism, reduced lesion volume and neuronal apoptosis, and improved neurological recovery with these effects abolished by miR-16-5p depletion.

Wen-Yuan Zhang, Ling Wang, Tao Zhang et al. · 0 citations

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