Review
Open access
Oct 2026
Beyond target presence: A cross-cancer contextual framework for siRNA therapeutics in solid tumors.
Small interfering RNA (siRNA) has achieved clinical success in liver-directed therapies, but its translation to solid tumors remains limited by heterogeneous delivery and context-dependent target dependence. This review compares non-small cell lung cancer, pancreatic ductal adenocarcinoma, breast cancer, glioblastoma,...
Na Zhao, Yang Zhang, Chao Qian et al.
· Biochimica et biophysica act... · 0 citations