Author

Lekshmi Rethi

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Review Aug 2026

Thymosin α-1 in Cancer Therapy: Immunomodulatory Mechanisms, Clinical Applications, and Translational Perspectives.

The biological functions, immunoregulatory mechanisms, and therapeutic potential of Tα1 in oncology are summarized to provide an updated perspective on the role of Tα1 as a potential adjunctive immunomodulatory agent in modern cancer immunotherapy.

Sih-Chi Chuang, Pei-Chia Hung, Lekshmi Rethi et al. · European Journal of Pharmaco... · 0 citations

Open access Sep 2026

A CD44-targeted PDA/ZnO redox-active nanocomposite that couples chemotherapy with mitochondrial stress and tumor immune remodeling

A reproducibly fabricated redox-active nanotherapeutic associated with mitochondrial stress that couples targeted chemotherapy with immune microenvironment remodeling for antitumor efficacy is established.

Andrew E.-Y. Chuang, Szu-Yu Tung, Kai-Yi Tzou et al. · Journal of Nanobiotechnology · 0 citations

Open access Jul 2026

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

The NIR‐activated platform is associated with reduced joint inflammation and edema, attenuated oxidative stress, improved macrophage polarization toward an anti‐inflammatory phenotype, enhanced gait‐related joint function, and preservation of cartilage structure in an OA rat model.

Yu-Wen Tseng, Pei-Wei Weng, Hsien-Tsung Lu et al. · Advanced Healthcare Material... · 0 citations