Serum Borrelia IgG as a rule-out test in suspected lyme neuroborreliosis: a large retrospective cohort study.
OBJECTIVES In Europe, the diagnosis of Lyme neuroborreliosis (NB) relies on intrathecal Borrelia burgdorferi sensu lato (Bbsl) antibody production, but this test has limited sensitivity in early disease and requires lumbar puncture (LP). We therefore evaluated the diagnostic performance of the quantitative LIAISON® ser...