Leo Gotoh

Acute trazodone treatment ameliorates behavioral abnormalities and improves subsequent short‐term memory in a lipopolysaccharide‐induced mouse model of acute brain dysfunction

Abstract Aim Systemic inflammation‐associated acute brain dysfunction, typified by delirium, is linked to later cognitive impairment. Although trazodone is used clinically for delirium‐related symptoms, its effects on subsequent cognition remain unclear. We examined whether acute‐phase trazodone treatment influences be...