Author

Leonard Maler

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Open access Sep 2026

Clustered heterogeneity, spiking history and efficient silencing maximize mutual information in adaptive time encoding

Neurons involved in a computation are remarkably diverse. They display a range of thresholds, time scales and spiking history dependence, and often exhibit adaptation that enhances computational power by concentrating spikes at transient stimuli. We seek basic organizational principles for coding with cellular heteroge...

Raphaël Lafond-Mercier, Leonard Maler, André Longtin · bioRxiv · 0 citations

Open access Jul 2026

Multiplexing of functionally distinct inputs by intrinsic modulation of spike timing in a monoaminergic nucleus.

This work shows that DRN 5-HT neurons exhibit separable spiking representations of two major excitatory inputs-those from the lateral habenula and the medial prefrontal cortex and confirms that this emergent population spike synchrony code provides a means for the DRN to widely broadcast these streams as a multiplexed...

M. Lynn, Leonard Maler, Jean-Claude Béïque · Cell Reports · 0 citations