Nanoscale Imaging and Proteomic Analysis Reveal a Tightly Regulated, Amorphous Granular Biopolymer Structure inside Bacteria.
Polyhydroxyalkanoates (PHAs) are biopolyesters that accumulate as cytosolic cell inclusions in many bacteria, enhancing resistance to environmental stresses. However, the structure, spatial localization, plasticization effects, and mechanical properties of PHA granules in vivo remain underexplored. Here, Cupriavidus ne...