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Author

Li-Bo He

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Open access Oct 2026

A double-stranded RNA fish reovirus activates cGAS-STING signaling and evades antiviral immunity through autophagy-mediated degradation

Double-stranded RNA (dsRNA) reoviruses are primarily sensed by the RIG-I-like receptor (RLRs) signaling pathway. However, whether these viruses can also activate the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, a central DNA-sensing system, remains poorly understood. Grass carp r...

Zi-Chao Peng, Fang Zhou, Xu-Yang Wang et al. · 0 citations
Review Jul 2026

Grass Carp Reovirus ( GCRV ): Biology, Immune Responses and Control Strategies

This research offers significant insights into viral cell invasion and strengthens innate and adaptive immunity, enabling safer, more practical and multilayered control in aquaculture.

Waqar Younas, Mi-Juan Shi, Rong Huang et al. · 0 citations

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