A double-stranded RNA fish reovirus activates cGAS-STING signaling and evades antiviral immunity through autophagy-mediated degradation
Double-stranded RNA (dsRNA) reoviruses are primarily sensed by the RIG-I-like receptor (RLRs) signaling pathway. However, whether these viruses can also activate the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, a central DNA-sensing system, remains poorly understood. Grass carp r...