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Open access Sep 2026

OmniTCR: a foundation model unifying T cell receptor recognition prediction and conditional sequence generation

T cell receptor (TCR) recognition prediction and receptor generation are traditionally modelled separately, leaving vast TCR sequence collections disconnected from smaller TCR–peptide–MHC datasets. Here we present OmniTCR, a 113-million-parameter autoregressive foundation model pretrained on 328 million formatted human...

Fei-Ran Zeng, Duanyu Feng, Dan-Dan Song et al. · 0 citations

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