Interplay between mitophagy, ferroptosis, and pyroptosis in acute pancreatitis: Regulatory mechanisms and therapeutic implications.
BACKGROUND With a very high death rate, acute pancreatitis (AP) is a frequent acute abdominal illness of the digestive system. It is challenging for the conventional notion of "trypsin self digestion" to adequately explain the molecular underpinnings of local inflammation that spreads across the body and the heterogene...