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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Li-Jun Ge

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3 papers indexed here

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Aug 2026

Artemisinin Attenuates Aβ1-42 Aggregation via the CaMK IV/PKA-CREB-Ace-H4 Cascade in Neuronal Cultures and 3xTg-AD Models.

Alzheimer's disease (AD), a progressive neurodegenerative disease with a rising global prevalence, is characterized by amyloid-β (Aβ) aggregation, tau hyperphosphorylation, inflammation, oxidative damage, and neuronal apoptosis. Studies have increasingly recognized epigenetic modifications as key regulators in the deve...

Yi-Tian Chen, Li-Jun Ge, Philip Lazarovici et al. · 0 citations
Sep 2026

Artemisinin Activates AMPK to Rescue Neuronal Cells and 3xTg Mice from Aβ1-42 Neurotoxicity.

It is demonstrated that ART confers robust neuroprotection primarily via AMPK activation, thereby restoring redox homeostasis, preserving mitochondrial structural integrity, and suppressing caspase-dependent apoptosis.

Yi-Tian Chen, Wen-Jun Xiong, Li-Jun Ge et al. · 0 citations
Review Open access Sep 2026

Research Progress on Bidirectional Regulation of the Microbiota–Gut–Brain Axis in Autism Spectrum Disorder Based on the Immune–Metabolic–Endocrine Interactive Network

Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder characterized by core features of social communication deficits and high prevalence of gastrointestinal comorbidities. With its continuously rising global prevalence, current therapeutic modalities remain unable to target and ameliorat...

Wei-Ao Kong, Hao-Ke Qiu, Yu-Hang Jiang et al. · 0 citations

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