Open access
Jul 2026
Cross-genus analysis reveals architecturally programmed sgRNA synthesis patterns in coronaviruses.
It is shown that canonical sgRNA formation is associated with same-direction RNA-RNA interactions, and this finding highlights a potential link between non-canonical sgRNAs, genomic plasticity, and immune modulation, which may have implications for coronavirus adaptation.
Zi Wen, Lei Chen, Dehua Luo et al.
· Molecular Systems Biology · 0 citations