Integrative multi-omics reveals that salvianolic acid a protects against septic liver injury by remodeling amino acid metabolism and redox homeostasis.
BACKGROUND Sepsis-induced liver injury (SILI) is a severe complication of sepsis associated with high morbidity and mortality. Salvianolic acid A (Sal A), a bioactive phenolic compound isolated from Salvia miltiorrhiza Bunge, exhibits hepatoprotective properties. However, its effects against SILI and underlying molecul...