Li Liao

ICM-MD: Integrating TM-specific features and MD-derived structures for accurate prediction of inter-chain contacts in α-helical transmembrane homodimers.

Characterizing the interactions of alpha-helical transmembrane homodimers at the residue level is crucial for understanding their structure and function. However, most computational tools are designed for globular proteins and fail to translate to transmembrane (TM) proteins, largely due to the unique environment of th...