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Open access Aug 2026

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

ABSTRACT Despite substantial progress in KRAS‐targeted therapies, specific inhibitors of the KRAS G13D mutant remain unavailable. In a retrospective analysis, we found a notable downregulation of glutathione peroxidase 2 (GPX2) in KRAS G13D‐ mutant colorectal cancer (CRC), which correlated with poor outcomes. We hypoth...

Xiaoting Liu, Chong Wu, Shiyao Song et al. · 0 citations
Aug 2026

The Combination of IVIM-DWI and BOLD-fMRI to Evaluate the Early Efficacy of Photodynamic Microenvironment-Modulating Therapy in Nasopharyngeal Carcinoma.

BACKGROUND Photodynamic microenvironment-modulating therapy (PMMT) represents a promising strategy for nasopharyngeal carcinoma (NPC). However, early assessment of therapeutic response remains challenging. PURPOSE To evaluate whether intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and blood oxygen...

Ping-Kang Chen, Li Ma, Zicong He et al. · 1 citation

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