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Author

Li-Min Cao

2 papers indexed here

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Open access Sep 2026

Matrix-Guided Size Selection of Plasmonic Nanoprobes for Improving Quantitative Robustness of SERS Lateral Flow Immunoassays

Surface-enhanced Raman scattering-based lateral flow immunoassays (SERS-LFIAs) have emerged as a promising platform for rapid food safety analysis. However, their quantitative reliability is often compromised by matrix-dependent variations during lateral flow, and the influence of probe size on analytical performance r...

Hao-Wei Liu, Hao Wang, Shuo Zhang et al. · 0 citations
Aug 2026

Structure-Guided CDR3 Insertion Enables Affinity Maturation of Naive Single-Domain Antibodies against Small-Molecule Haptens.

A "structure-guided directed modification" strategy was developed that focuses on conformational tuning rather than simple side-chain replacement to overcome the structural and energetic barriers inherent in hapten recognition and provide a practical and efficient computational framework for assisting the rapid evoluti...

Zeng-Lin Yang, Guo-Qiang Li, Yuanyuan Ge et al. · 0 citations

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