Author

Li-Min Rong

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Open access Sep 2026

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

ABSTRACT In adult mammals, poor functional recovery after spinal cord injury (SCI) is largely due to the very limited capacity to reconstruct damaged neural connections together with neuronal loss. Here, we identify the neuroprotective role of Zdhhc17 as a palmitoyl acyltransferase (PAT) following SCI. Neuron‑specific...

Mei-Xuan Chen, Huan Chen, Si-Ning Ding et al. · Advancement of science · 0 citations

Open access Jul 2026

Clinical trial landscape of cell therapy for spinal cord injury: from integrated practices to future developments

Clinical trials for SCI were mapped to quantify patient demographic parameters, identify lineage-specific adverse-event patterns, evaluate objective motor and sensory efficacy outcomes, and analyze methodological trial designs to formulate concrete structural recommendations for future advanced-phase trials.

Jun Kang, Sen-Yu Yao, Song-Fu Zou et al. · BMC Medicine · 0 citations

Jul 2026

PLIN2-PGAM5-regulated lipid droplet-mitochondria contacts drive microglial neuroinflammation after spinal cord injury via fatty acid metabolic reprogramming.

The findings identify the PLIN2-PGAM5 as a critical metabolic-immune pathway and suggest that targeting organelle-contact-mediated metabolic reprogramming represents a potential therapeutic strategy for CNS injury.

Daoqiang Huang, Hong Li, Yiqian Luo et al. · Cell Death and Differentiati... · 2 citations