Review
Aug 2026
Engineered coacervates as emerging liquid biomaterials
Bo Yi, Jian-Yang Zhao, Qing-Qiao Xie et al.
· Nature Reviews Materials · 0 citations
3 papers indexed here
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Open access
Sep 2026
Viscoelastic hydrogel potentiates cancer cell stemness and drug resistance through Piezo1‐dependent mechanotransduction
The dynamic mechanical properties of the tumor microenvironment are crucial for cancer progression, yet their specific effects independent of matrix stiffness remain unclear. Here, we develop a hydrogel system with tunable viscoelasticity based on reversible host–guest crosslinking that decouples network dynamics fro...
Yi Liu, Hui-Yao Deng, Han-Lei Zhang et al.
· BMEMat · 0 citations
Aug 2026
Mechanical regulation of m6A-dependent autophagy sustains cancer stemness and chemoresistance in a viscoelastic tumor microenvironment.
The mechanical properties of the tumor microenvironment fundamentally influence cancer progression, while how viscoelastic cues interface with epitranscriptomic regulation to control cell fate remains poorly understood. Here, a pair of hyaluronic acid-based supramolecular hydrogels with tunable network dynamics are eng...
Yue-Man Zhang, Chu-Tian Huang, Yu-Xiao Zhang et al.
· Biomaterials · 0 citations