Auditory brainstem response deficits precede and are associated with subsequent auditory cortical amyloid burden in male APP/PS1 mice.
BackgroundAuditory dysfunction is considered one of the early manifestations of Alzheimer's disease (AD). However, its evolutionary characteristics with the progression of AD have not been fully studied, and the temporal relationship between this sensory impairment and the typical pathology of the disease is unclear.Ob...