Li-Qun Wei

An adenovirus-based multiantigen vaccine protects against tuberculosis by coordinating adaptive immunity and curbing immunosuppressive mechanisms

The identification of a multi-antigen vaccine candidate, Ad-8CPR2, as the most immunogenic construct, which incorporates M. tuberculosis antigenic proteins with strong immunogenicity and functional properties, which are fused with peptide segments capable of augmenting antigen-specific immune responses.