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Li Tang

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Open access Aug 2026

Comparative systemic pathogenicity and host tropism of ancestral SARS-CoV-2, Delta, and Omicron EG.5 variants in K18-hACE2 mice

This study provides direct experimental evidence for a pronounced attenuation in pathogenicity along the evolutionary trajectory from Wild-type through Delta to Omicron EG.5.5, and offers crucial insights for risk assessment of emerging variants.

Xiaofang Peng, Qi Zhang, Pingping Zhou et al. · 0 citations