Author

Li-Xiang Sun

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Open access Oct 2026

TRIM28 Increases RFC4 Protein Expression to Promote Triple‐Negative Breast Cancer Progression

ABSTRACT Replication factor C subunit 4 (RFC4) dysregulation has been implicated in tumor progression and poor prognosis across multiple cancer types. Triple‐negative breast cancer (TNBC) is an aggressive subtype with limited treatment options and poor outcomes, underscoring the need for effective therapeutic targets....

Cheng Guo, Li Liu, Li-Xiang Sun et al. · MedComm · 0 citations

Open access Sep 2026

STAT5A-RNF8 signaling regulates homologous recombination repair and cisplatin responsiveness in cervical cancer.

Cisplatin resistance remains a major limitation in the treatment of cervical cancer, with enhanced DNA damage repair contributing to reduced therapeutic sensitivity. The role of STAT5A in coordinating DNA double-strand break repair under therapeutic stress remains unclear. Here, we investigated the role of STAT5A in ci...

Wei-Hong Lu, Wei-Ping Wang, Li-Xiang Sun et al. · Neoplasia · 0 citations