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Open access Aug 2026

Multi-omics analysis of histidine metabolism reveals FRZB-CRYM-associated cellular crosstalk in heart failure

This study systematically characterizes the potential role of histidine metabolism dysfunction in HF and supports a model of a putative “stroma-myocardium” positive feedback loop associated with FRZB (in stromal cells) and CRYM (in cardiomyocytes).

Songlin Xiao, Chun-Lei Mo, Qi-Xing Liu et al. · 0 citations

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