Author

Li-Yan Yang

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Open access Sep 2026

Small-Molecule Drugs Approved by the FDA in 2025

In today’s pharmaceutical sector, innovation is not only the core driver of industry upgrading, but also closely tied to patient health and well-being. A drug’s innovative mechanism of action, physiological effects, chemical structure, and indications collectively reflect both its clinical therapeutic value and the nov...

Xiao-Yue Wang, Ying Wang, Rui-Kang Luo et al. · Molecules · 0 citations

Review Open access Sep 2026

TRAIL of Hope: Bioactive Dietary Component-Driven Carrier-Free Nanoplatforms for Synergistically Enhanced Tumor Multimodal Therapy

Abstract Considering the inherent drawbacks of conventional anticancer drugs, such as suboptimal efficacy and undesirable toxicity, functional dietary components have been increasingly focused on achieving optimal therapeutic performance and minimizing side effects. A combination of nanoscience and drug delivery gave b...

Li-Yan Yang, Xian-Qing Song, Zhong-Lei Wang · International Journal of Nan... · 1 citation

Review Aug 2026

Chemical scaffolds, structure-activity relationships, and therapeutic potential of EphA2 small-molecule inhibitors.

This review provides a comprehensive overview of the research progress of EphA2-targeted small-molecule inhibitors reported to date, systematically summarize their representative chemical scaffolds, structure-activity relationships, binding modes, and pharmacological profiles, and highlight the current challenges in se...

Li-Yan Yang, Jun He, Wenjing Xiao et al. · European journal of medicina... · 0 citations