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Li-Ying Chen

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Open access Sep 2026

MINT infers the latent single-cell spatial transcriptome from paired histology

Sequencing-based spatial transcriptomics captures transcriptome-wide molecular information, yet the corresponding cell-resolved tissue map remains incomplete. Histology records dense cellular morphology, tissue architecture and local context. Here, we present MINT (Morphological Integrative Network for Transcriptomics)...

Li-Ying Chen, Zhong-Min Zhang, Bing Wang et al. · 0 citations
Open access Sep 2026

CMTM6/PD-L1-targeted AAV promotes anti-tumor immune responses and chemotherapy responsiveness

Chemotherapy is one of the important clinical treatments for malignant tumors, but primary or acquired chemotherapy resistance significantly limits patient benefits. Programmed death ligand 1 (PD-L1) has been reported to be regulated by chemotherapy and to contribute to chemotherapy resistance. However, as a novel regu...

Run-Qiu Chen, Xiao-Yu Pang, Fang-Lin Li et al. · 0 citations

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