Integrated murine and human transcriptomics prioritizes a multicellular mitochondrial signature associated with immune and parenchymal features in NAFLD/MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD), historically termed nonalcoholic fatty liver disease (NAFLD), involves metabolic dysregulation, mitochondrial stress, and immune remodeling. However, disease-associated multicellular transcriptional programs and their spatial context remain incompletel...