Li-Zhi Chen

Annotation of Cell Types in Single-Cell Sequencing for Cardiovascular Disease: Concepts, Workflows, Challenges, and Best Practices.

Single-cell and single-nucleus RNA sequencing (scRNA-seq and snRNA-seq) have transformed cardiovascular biology by resolving cellular heterogeneity and disease-specific cell states. The interpretive power of these technologies, however, hinges critically on accurate cell-type annotation, the assignment of biologically...