Open access
Sep 2026
Estradiol Promotes Tumor Progression in ERα‐Low Endometrial Cancer via the GPER/SphK1 Pathway
Endometrial cancer (EC) is the most common gynecological malignancy in postmenopausal women. Patients with low estrogen receptor alpha (ERα) expression frequently develop aggressive pathological subtypes and have poor prognosis. The role of estradiol (E2) in ERα‐low EC remains poorly understood. This study investigated...
Xiu-Wen Wang, Hao-Fei Sun, Xin Wen et al.
· Journal of biochemical and m... · 0 citations