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Author

Liam McFarlane

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Open access Oct 2026

PGC1α/SIRT3-Mediated Oxidative Stress and Downregulation of NLRP3 Expression by Sodium Thiosulfate Pre- and Post-Treatment Accelerates Recovery from Ischemia–Reperfusion-Induced Acute Kidney Injury

Background: Renal ischemia–reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). It is associated with reduced blood flow as encountered in vascular surgery, including aortic aneurysm repair and kidney transplantation. In this study, we investigated whether pre- and/or post-administration of sodiu...

George J. Dugbartey, Liam McFarlane, T. Shamma et al. · 0 citations

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