Lian-Hui Zhang

Receptor-like kinase RLK15 binds a fungal RNase effector to enhance autophosphorylation and activate host defense

RdmB Activates the Quorum Quenching Activity of Pseudomonas nitroreducens HS-18 by Direct Regulating Two Sets of DSF Signal Degradation Enzymes.

Many pathogenic bacteria produce diffusible signal factor (DSF) quorum sensing (QS) signals to regulate virulence. Quorum quenching (QQ) frequently interferes with QS via enzymatic signal degradation to alleviate pathogenicity. However, DSF-targeted QQ regulatory mechanisms remain largely vague. Recently, we reported t...

Pseudomonas shiyinii ST4 inhibits sexual mating of Sporisorium scitamineum through the GacS/GacA two-component system and the mib1 gene cluster

ABSTRACT Sugarcane smut is one of the most devastating fungal diseases affecting sugarcane plantations. The virulence of the causative agent, Sporisorium scitamineum, depends on a process called sexual mating of compatible sporidia MAT-1 and MAT-2 to form infectious dikaryotic hyphae. We previously isolated Pseudomonas...

Marine antifouling biocide 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one disrupts sediment microbiome structure and function: insights from absolute quantification and enzyme activity dynamics

Analysis of microbial responses to DCOIT exposure over 30 days demonstrates that DCOIT poses microbial ecological risks beyond toxicity to macroorganisms and should be considered in assessments of antifouling biocides.

Spermidine targets GGA-rich small RNAs for virulence regulation

Summary Spermidine (SPD), a polyamine essential for various biological processes, has long been recognized as a signaling molecule. Yet, its specific molecular targets and mechanisms of action remain elusive. In this study, we uncover a previously unknown mechanism whereby SPD selectively binds to small regulatory RNAs...