Introduction Chimeric antigen receptor (CAR)-T cell therapy has achieved remarkable success in hematologic malignancies, prompting its exploration in solid tumors. This systematic review and meta-analysis aimed to evaluate the safety and feasibility of CAR-T therapy for solid tumor treatment. Methods We systematically...
Kun-Peng Wang, Lian Li, Zhang-Neng Yu et al.· Frontiers in Immunology· 0 citations
Renal impairment (RI) increases mortality risk in multiple myeloma (MM), yet RI represents a relatively late stage of kidney dysfunction. Whether early indicators of renal dysfunction, such as the estimated glomerular filtration rate (eGFR slope), predict mortality risk in MM remains unknown.
Lian Li, Xiang Liu, Ming-Jing Guan et al.· Cancer Medicine· 0 citations
The persistent emergence of resistance underscores that current targeted therapies, while revolutionary, are primarily disease-modifying rather than curative, necessitating continuous innovation to overcome the inherent biological challenge of tumor adaptability and heterogeneity.
Gu-Ha A-Lai, Lian Li, G. Ma et al.· Frontiers in Cell and Develo...· 0 citations
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