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Lianzhong Ai

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Open access Sep 2026

Ligilactobacillus salivarius AR809 and its exopolysaccharides mitigate antibiotic-induced gut dysbiosis and restore intestinal barrier function

Gut microbiota dysbiosis is closely associated with intestinal barrier dysfunction and immune imbalance. This study evaluated the efficacy of Ligilactobacillus salivarius AR809 and its exopolysaccharides (EPS809) in alleviating dysbiosis-associated intestinal dysfunction. In an antibiotic-induced murine model, both...

Shen Li, Yao Chen, Yong-Jun Xia et al. · 0 citations
Review Jul 2026

Dietary Polysaccharides Modulate Interactions between Bacteroides and the Gut Microbiota: Gene-Level Mechanisms and Perspectives on Genome-Scale Metabolic Modeling for Community Simulation.

Bacteroides is a major gut genus involved in polysaccharide uptake and degradation, yet the gene-level mechanisms by which dietary polysaccharides modulate interactions between Bacteroides and other gut microbes remain insufficiently integrated. This review summarizes dietary-polysaccharide-driven Bacteroides interacti...

Yueyi Zhang, Xin Song, Lianzhong Ai et al. · 1 citation
Jul 2026

Functional role of the diadenylate cyclase gene cdaA in stress responses of the dairy starter Streptococcus thermophilus.

Results showed that cdaA is critical for osmotic and ethanol tolerance but negatively modulates bile salt resistance in S. thermophilus, suggesting that absence of cdaA confers a survival advantage under bile salt stress.

Yizhou Fan, Xinxin Liu, Xin Song et al. · 0 citations

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