Review
Open access
Aug 2026
The cGAS/STING pathway in cancer: translating innate DNA sensing into therapeutic potential
How context determines the consequences of cGAS/STING activation in cancer is examined, emerging therapeutic strategies that modulate this pathway are reviewed, and how its antitumor potential can be maximized while minimizing systemic toxicity and immune dysregulation is discussed.
Yi Wang, J. Angulo-Lozano, Yueqi Wang et al.
· Journal of Clinical Investig... · 0 citations