Sep 2026
Dual-drug conjugated ionizable lipids for nucleic acid delivery and multidimensional targeted therapy of brain tumors.
Lipid nanoparticles (LNPs) are the leading non-viral platform for nucleic acid delivery, and the structural design of ionizable lipids critically determines their delivery efficiency and therapeutic potential. Here, a dual-functional ionizable lipid was developed by integrating a vinpocetine-derived neurovascular regul...
Yue-Yue Sun, Dan-Dan Huang, Yue Qing et al.
· International journal of pha... · 0 citations