Background Triple-negative breast cancer (TNBC) remains highly aggressive and lacks effective molecularly targeted therapies. Programmed death-ligand 1 (PD-L1) represents a potential cell-surface target for selective drug delivery. Objective To develop and evaluate a PD-L1 aptamer–functionalized mesoporous silica nanop...
Jun-Tao Tan, Zi-Xi Hu, Da Huang et al.· International Journal of Nan...· 0 citations
Findings provide proof-of-concept support for further evaluation of activatable AS1411-based probes for molecular imaging of nucleolin-overexpressing TNBC and enable preferential, high-contrast fluorescence imaging in the tested MDA-MB-231 TNBC model across in vitro, in vivo, and ex vivo experiments.
Jun-Tao Tan, Zi-Xi Hu, Da Huang et al.· Frontiers in Bioengineering...· 0 citations
Electrochemical two-electron water oxidation (2e-WOR) offers a promising direct route to on-site hydrogen peroxide (H2O2) production, yet state-of-the-art catalysts still suffer from intrinsically low selectivity and large overpotentials, especially in near-neutral media. Equally unresolved is how the electrolyte compo...
Ming-Yu Liu, Shao-Wei Mei, Muhammad Afsar Khan et al.· Small· 0 citations
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