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Liangming Chen

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Sep 2026

A Teleost - Specific Sema4E - like Protein Promotes Grass Carp Reovirus Infection by Upregulating HSP70 Expression.

Hemorrhagic disease caused by grass carp reovirus (GCRV) poses a severe threat to the grass carp aquaculture industry. Semaphorin 4E-like (Sema4E-like), a teleost-specific signaling molecule, remains poorly understood in immune regulation. In this study, the grass carp Sema4E-like gene was cloned and characterized, rev...

Yu-Huan Shao, Jin-Yan Lei, Ju-Hong Xie et al. · 0 citations
Jul 2026

Thioredoxin 1 inhibits GCRV replication by maintaining redox homeostasis in grass carp (Ctenopharyngodon idella).

Findings suggest that trx1 acts as an important antiviral regulator that maintains intracellular redox homeostasis and contributes to host protection against GCRV infection by limiting oxidative stress, apoptosis, and excessive inflammatory responses.

Denghui Zhu, Xiao-Ya Wang, Liangming Chen et al. · 0 citations

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