Open access
Sep 2026
An Integrated Multi-Tissue Single-Cell Transcriptomic Analysis Highlights the CCL2-CCR2 Signaling Pathway as a Potential Therapeutic Target in Neuropathic Pain
Background Neuropathic pain involves complex neuroimmune interactions across the somatosensory nervous system, yet a comprehensive multi-tissue cellular landscape remains lacking. Methods We integrated single-cell RNA sequencing data from the sciatic nerve (SN), dorsal root ganglion (DRG), and spinal cord (SC) of spare...
Xiao-Feng Gan, Kai-Long Wang, Dong-Ming Lu et al.
· Journal of Pain Research · 0 citations